As runners get ready to lace up for the Three Sisters Marathon races on Friday, Sept. 5, and Saturday, Sept. 6, there are several street closures to keep in mind.

If you’re driving northbound on Route 609 in Henry County, save yourself some time.

Both crashes have been cleared, according to VDOT.

If you’re driving northbound on I-81 in Montgomery County, expect delays.

If you’re driving northbound on I-81 in Roanoke County, expect delays.

If you’re driving southbound on Interstate 81 in Botetourt County, save yourself some time.

The scene of this vehicle fire has been cleared, according to VDOT.

All of Route 220 (Franklin Road) in Roanoke County is now open, according to the police department.

The scene of this crash has been cleared, according to VDOT.

Starting Thursday, July 24, milling and paving operations will take place on Coffee Road, specifically from Wildwind Place to Walnut Hollow Road.

Drivers are asked to avoid Walnut Avenue and Jefferson Street due to a vehicle crash.

Heads up, drivers! The City of Danville has closed Lynn Street, between DeBoe Street and Jackson Street, for construction purposes.

If you plan on driving through downtown Roanoke on Wednesday or Thursday, there is a road closure you’ll want to be aware of.

Heavy rain has caused significant damage to a section of U.S. 58 eastbound in Halifax County, according to VDOT.

The first phase of the Apperson Drive Bridge Replacement Project kicks off on Tuesday, June 24, and you’re urged to plan alternate routes if you can.

If you’re driving eastbound on Route 622 near Greendale Drive in Campbell County, save yourself some time.

Heads up, drivers! Bridge work is set to start taking place overnight on I-81 near Staunton, and it could affect your commute.

If you’re driving northbound on Route 311 in Alleghany County, expect delays!

Heads up, drivers! A vehicle crash on Route 757 eastbound in Bedford County is causing delays.

If you’re driving southbound on US-29 in Campbell County, save yourself some time!

If you’re driving on Route 721 in Bedford County, expect delays!

Northbound Interstate 81 is closed near Staunton due to a tractor-trailer crash at mile marker 224.

If you’re driving on I-81S in Montgomery County, expect delays.

Drivers are being asked to avoid the intersection of Challenger Avenue and Cloverdale Road after a car crashed into a utility pole as it was headed east.

If you’re headed westbound on Route 460 in Botetourt County, save yourself some time!

If you’re driving in Roanoke County Thursday morning, please use caution. The Roanoke County Communications is reporting nearly 50 roads that are closed due to downed trees or power lines.

Drivers are asked to avoid Route 220 at Starlight Lane in Roanoke County as police respond to the scene of a tree down in power lines.

This crash has been cleared, according to VDOT.

Heads up, drivers! A tractor-trailer crash on Interstate 81 southbound in Roanoke County is causing delays, according to VDOT.

If you’re driving southbound along I-77 in Wythe County, save yourself some time!

One person was hospitalized after a crash in Northwest Roanoke on Monday morning, according to Roanoke Fire-EMS.

If you’re headed toward I-81N in Rockbridge County, expect delays.

If you’re driving along I-81N in Roanoke County, expect delays!

Attention, drivers! There will be detours in place as crews work to remove railroad tracks from two highly traveled intersections in Salem.

If you frequently travel along Orange Avenue, there are two different construction projects you should be aware of.

If you frequently travel along Orange Avenue, there are two different construction projects you should be aware of.

Heads up, drivers! An extended ramp closure on I-81S at exit 141 has been scheduled for this weekend, starting Friday at 8 p.m. as deep mill paving work gets underway.

The scene of this vehicle fire has been cleared, according to VDOT.

If you’re headed north along Route 220 in Franklin County, expect delays!

The scene of this incident has been cleared, according to VDOT.

There is a crash on I-81 in Botetourt County.

A gas leak has temporarily shut down part of Lake Vista Drive in Forest, according to the Forest Fire Department.

This has been cleared, according to VDOT.

This crash has been cleared, according to VDOT.

This crash has been cleared, according to VDOT.

Lynchburg drivers are being asked to avoid the area of Thomson Drive and Tate Springs Road near Centra Hospital due to down power lines in the area.

Drivers heading north on US-220 in Roanoke can expect delays due to a multiple-vehicle crash from Franklin Road SW to Elm Avenue SE.

Drivers heading south on Interstate 81 in Roanoke County can expect delays due to a tractor-trailer crash.

The crash on I-81 Northbound in Botetourt County has been cleared

The scene of this crash has been cleared, according to VDOT.

This crash has been cleared, according to VDOT.

The vehicle crash that occurred on US-220 Northbound has been cleared, according to VDOT.

This crash has been cleared, according to VDOT.

Virginia State Police have confirmed that a 44-year-old died in an officer-involved shooting that happened after a police chase that started in Giles County and ended in Montgomery County on Tuesday.

A vehicle fire on Route 685 in Campbell County is causing delays, according to VDOT.

This crash has been cleared, according to VDOT.

Starting at 8 p.m. Thursday, only one southbound lane will be open between mile markers 136 and 138.

The vehicle fire has been cleared, according to VDOT.

Drivers on Interstate 81 in Roanoke County can expect delays due to a tractor-trailer crash.

The multi-vehicle crash and disabled vehicle have been cleared, according to VDOT.

This crash has been cleared, VDOT said.

The Wasena Bridge in Roanoke is set to close Monday, April 22 as construction gets underway to build a new bridge.

Two people are in the hospital after a crash on I-581N in Roanoke, according to the Roanoke Police Department.

A driver was hospitalized and charges are pending after a crash in Northwest Roanoke, according to the Roanoke Police Department.

Drivers heading south on Interstate 81 in Roanoke County can expect delays due to a tractor-trailer crash.

Drivers heading north on Interstate 81 in Roanoke County can expect delays due to a tractor-trailer crash.

Virginia State Police are investigating an incident on Trents Ferry Road in Bedford County.

Those driving south along Interstate 81 in Rockbridge County should anticipate delays.

VDOT is warning drivers about a tractor-trailer crash that is slowing down traffic on US-58 in Henry County.

Drivers heading north on Interstate 81 in Montgomery County can expect delays due to a multi-vehicle crash.

Drivers headed north on Interstate 81 in Roanoke County can expect delays due to a vehicle crash.

A Roanoke County crash on Interstate 81 southbound is slowing down traffic, according to VDOT.

A tractor-trailer crash on US-220 northbound near the intersection of Route 619 in Franklin County is causing delays, according to VDOT.

Virginia State Police is investigating a fatal crash in Wise County that left a 73-year-old dead.

A portion of Yellow Mountain Road is currently blocked to traffic due to a downed tree that damaged several utility poles, according to the Roanoke County Police Department.

If you’re headed toward I-81 southbound in Roanoke County, find another route if you can.

Two people were hospitalized with minor injuries and another was charged following a morning crash on Orange Avenue, according to the Roanoke Police Department.

Roanoke Police said the tree has been removed and the road is now clear.

A disabled vehicle on Interstate 581 is making the evening commute a bit slower than normal for drivers headed south.

This crash has been cleared, according to VDOT.

Drivers headed north on Interstate 81 in Rockbridge County can expect delays due to a tractor-trailer crash.

This incident has been cleared, according to VDOT.

If you’re hitting the road Monday morning, you might want to avoid I-81 northbound in Pulaski and Montgomery Counties.

This crash has been cleared, according to VDOT.

The bridge over Pigg River on Snow Creek Road is closed until further notice, according to the Franklin County Department of Public Safety.

If you’re driving along US-460 in Campbell County, expect delays.

Drivers heading south on Interstate 81 in Roanoke County can expect delays due to a vehicle crash.

If you’re driving along Rt. 757 in Bedford County Tuesday morning, proceed with caution.

Virginia State Police told 10 News that there were a total of seven weather-related crashes Tuesday morning in Alleghany, Bath and Highland, three of which happened on Interstate 64.

The Roanoke Police Department says a water main break has closed a portion of Roundhill Avenue in Northwest Roanoke.

With winter weather rolling through much of Central and Southwest Virginia, there are now a few road closures in place due to icy conditions.

A tractor-trailer crash on Interstate 81 in Botetourt County is causing delays, according to VDOT.

According to Virginia 511, there is no longer congestion in the area due to emergency roadwork or vehicle fire.

A tractor-trailer crash on Interstate 81 is causing delays in Botetourt County, according to VDOT.

If you’re driving along Interstate 81 southbound in Roanoke County, a vehicle crash could slow down your morning commute.

If you’re hitting the road for Thanksgiving weekend, anticipate delays on I-81 northbound in Rockbridge County.

The area is now clear, according to VDOT.

The area is now clear, according to Virginia 511.

Drivers heading south on I-81 in Roanoke County can expect delays due to a vehicle crash.

A vehicle crash on US-460 in Montgomery County could impact your morning commute, according to VDOT.